Botulinum toxin, or Botox, is a powerful protein that can help stop muscle spasms. It is injected directly into the muscle, and the effects are usually temporary but can last for several months. The number of injections needed depends on the area being treated and other factors.
Botox
works by blocking nerve signals to the muscles, preventing them from contracting.Injections are usually done in a doctor's office, using a fine needle to inject small amounts of botulinum toxin. The muscle injected depends on the main area of concern, and several areas can be treated in one session. If you experience any difficulty breathing, swallowing, or talking after receiving Botox injections, contact your doctor right away. In practice, doctors often use an intradermal injection for this purpose, as it is believed to have a lower risk of adverse effects than intramuscular injection.
The total recommended dose for spasticity is divided into multiple injections into the affected muscles. For HAV and urinary incontinence caused by a neurological condition, Botox is given by intradetrusor injection.
Botox
binds irreversibly to receptors on presynaptic nerve terminals and is absorbed at the nerve terminal. Side effects such as ptosis of the eyebrows, heaviness of the eyebrows, and difficulty performing facial expressions were more prominent on the side of the IM injection.In one study, 25 out of 27 people who used Botox improved their condition within 48 hours after receiving the drug. However, some cases of hair loss have been reported since Botox was approved for use and became available on the market. In some cases, it may be recommended to use weekly casts of a joint for several weeks (serial plaster) after giving the injections. It is possible that these clinical differences are due to disparity in the initial severity of wrinkles, not to injection techniques. To treat this type of urinary incontinence, Botox is injected directly into the detrusor muscle of the bladder.
Botox contains onabotulinumtoxinA, which is a complex that contains botulinum toxin type A in addition to other proteins. In this pilot study, the anti-wrinkle effect of BTXA was not significantly different between the IM injection and the ID injection for the three participants. A previous split-face study concluded that there are no beneficial effects of ID BTXA compared to normal saline injection.2 If you choose botulinum toxin injections, you will need to undergo treatment every three to six months to maintain optimal results. Overall, Botox injections can be an effective way to reduce muscle spasms and improve certain medical conditions. However, it's important to understand all potential risks before undergoing treatment. Talk to your doctor about any concerns you may have and make sure you understand all possible side effects.
